Description

[(Olean-12-En-3β-Yl)Oxy]Trimethylsilane is a high-purity organosilicon derivative of oleanolic acid, a key triterpenoid scaffold. This compound is specifically engineered to introduce a silyl protecting group, which is critical for enhancing solubility and enabling selective synthetic modifications in complex organic syntheses. It serves as a valuable advanced intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the development of novel bioactive compounds and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel triterpenoid-based drug candidates, including anti-inflammatory and antiviral agents.
• Agrochemical Research: Used in the development of new plant growth regulators and bioactive agrochemicals with modified properties.
• Chemical Derivatization: Enables the protection of the 3β-hydroxy group in oleanolic acid, allowing for further selective functionalization at other reactive sites on the molecule.
• Material Science: Serves as a precursor for creating functionalized surfaces or polymers with specific biological or chemical activities.
• Academic & R&D Laboratories: Essential reagent for synthetic organic chemistry research focused on natural product modification and medicinal chemistry.

Basic Information

Product Name	[(Olean-12-En-3β-Yl)Oxy]Trimethylsilane
CAS No.	1721-67-1
Molecular Formula	C33H56O2Si
Molecular Weight	512.89 g/mol
Synonyms	Oleanolic Acid 3-Trimethylsilyl Ether; 3β-[(Trimethylsilyl)oxy]olean-12-en-28-oic Acid (ambiguous, often refers to methyl ester); Olean-12-en-3β-ol, trimethylsilyl ether; Oleanolic Acid TMS Ether; 3-Trimethylsiloxyolean-12-ene; TMS-Oleanolic Acid; (3β)-Olean-12-en-3-yloxy(trimethyl)silane
EINECS	Contact for details

Quality Control

Our [(Olean-12-En-3β-Yl)Oxy]Trimethylsilane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing batch-specific results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong alkali and incompatible organic solvents. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.