Description

[2-(4-Fluoro-Phenyl)-Pyrimidin-5-Yl]-Methanol is a high-purity fluorinated pyrimidine derivative, a crucial advanced pharmaceutical intermediate (API) for modern drug discovery and development. Its value lies in its precise molecular architecture, which serves as a versatile building block for synthesizing targeted therapeutic agents. This compound is essential for research and production in the pharmaceutical and agrochemical industries, particularly for developing kinase inhibitors and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors targeting various cancers and inflammatory diseases.
• Agrochemical Research: Used in the development of novel herbicides and fungicides, leveraging the bioactivity of the pyrimidine core.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization in medicinal chemistry, enabling the creation of compound libraries for high-throughput screening.
• Life Science Research: Employed in academic and industrial R&D for studying biochemical pathways and developing new therapeutic candidates.
• Material Science: Potential use in the synthesis of specialty chemicals and functional materials due to its aromatic and heterocyclic structure.

Basic Information

Product Name	[2-(4-Fluoro-Phenyl)-Pyrimidin-5-Yl]-Methanol
CAS No.	960198-65-6
Molecular Formula	C11H9FN2O
Molecular Weight	204.20 g/mol
Synonyms	(4-Fluorophenyl)-5-pyrimidinemethanol; 5-(Hydroxymethyl)-2-(4-fluorophenyl)pyrimidine; 2-(4-Fluorophenyl)-5-pyrimidinemethanol; [2-(4-Fluorophenyl)pyrimidin-5-yl]methanol; 960198-65-6; (2-(4-Fluorophenyl)pyrimidin-5-yl)methanol
EINECS	Contact for details

Quality Control

Our [2-(4-Fluoro-Phenyl)-Pyrimidin-5-Yl]-Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.