Description

1-[4-(Trifluoromethyl)Phenyl]Cyclopropane-Carbonyl Chloride is a high-purity, reactive organic intermediate characterized by its cyclopropane and trifluoromethylphenyl functional groups. This compound is a critical building block in advanced organic synthesis, enabling the efficient introduction of a sterically constrained, fluorinated aromatic moiety into target molecules. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used to construct advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of novel polymers and liquid crystals with unique thermal and optical properties.
• Fluorinated Compound Library Synthesis: Essential for medicinal chemistry programs focused on building diverse compound libraries for high-throughput screening.

Basic Information

Product Name	1-[4-(Trifluoromethyl)Phenyl]Cyclopropane-Carbonyl Chloride
CAS No.	960071-10-7
Molecular Formula	C11H8ClF3O
Molecular Weight	248.63 g/mol
Synonyms	1-[4-(Trifluoromethyl)phenyl]cyclopropanecarbonyl chloride; 4-(Trifluoromethyl)cyclopropanecarboxyphenyl chloride; Cyclopropanecarbonyl chloride, 1-[4-(trifluoromethyl)phenyl]-; α-(4-Trifluoromethylphenyl)cyclopropanecarbonyl chloride; (4-Trifluoromethylphenyl)cyclopropanecarboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 1-[4-(Trifluoromethyl)Phenyl]Cyclopropane-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.