Description

(4-Iodo-3-Trifluoromethyl-Phenyl)-Methanol is a high-purity, multi-functional aromatic building block featuring iodine and trifluoromethyl substituents. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, enabling the introduction of both halogen and fluorine-containing groups into target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting receptor modulation.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, where the iodine and trifluoromethyl groups can enhance biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in cross-coupling and other transition metal-catalyzed reactions.
• Material Science Research: Employed in the synthesis of functionalized monomers or additives for advanced polymers and electronic materials.
• Fluorine Chemistry: An important building block for introducing the trifluoromethyl moiety into more complex fluorinated compounds of industrial interest.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	(4-Iodo-3-Trifluoromethyl-Phenyl)-Methanol
CAS No.	959632-19-0
Molecular Formula	C8H6F3IO
Molecular Weight	302.04 g/mol
Synonyms	4-Iodo-3-(trifluoromethyl)benzyl alcohol; (4-Iodo-α,α,α-trifluoro-m-tolyl)methanol; 1-Iodo-4-(hydroxymethyl)-2-(trifluoromethyl)benzene; 3-Trifluoromethyl-4-iodobenzyl alcohol; m-Trifluoromethyl-p-iodobenzyl alcohol; 4-Iodo-3-trifluoromethylbenzenemethanol; 959632-19-0; 4-Iodo-α,α,α-trifluoro-m-toluyl alcohol
EINECS	Contact for details

Quality Control

Our (4-Iodo-3-Trifluoromethyl-Phenyl)-Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with full batch traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.