Description

Tetraethyl(Troc-Aminomethylene)Bisphosphonate is a specialized organophosphorus compound featuring a Troc-protected aminomethylene linker, serving as a critical building block in advanced organic synthesis. This bisphosphonate derivative is engineered to provide controlled reactivity, making it essential for constructing complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel bisphosphonate-based drug candidates, particularly for targeting bone metabolism disorders.
• Ligand Synthesis: Used to create complex chelating agents and ligands for catalysis and metal ion sequestration.
• Prodrug Development: The Troc (2,2,2-trichloroethoxycarbonyl) protecting group allows for the design of targeted prodrugs with specific release mechanisms.
• Agrochemical Research: Intermediate in the development of new herbicides and plant growth regulators with enhanced efficacy.
• Material Science: Building block for functionalized polymers and surface-modifying agents.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	Tetraethyl(Troc-Aminomethylene)Bisphosphonate
CAS No.	959581-96-5
Molecular Formula	C12H24Cl3NO8P2
Molecular Weight	494.62 g/mol
Synonyms	Tetraethyl [(2,2,2-trichloroethoxycarbonylamino)methylene]bisphosphonate; Troc-AMBP; (Aminomethylene)bisphosphonic acid tetraethyl ester, N-Troc-protected; Phosphonic acid, P,P'-[[(2,2,2-trichloroethoxy)carbonyl]amino]methylene]bis-, tetraethyl ester; Tetraethyl N-[(2,2,2-trichloroethoxy)carbonyl]aminomethylenediphosphonate; Troc-protected aminomethylenebisphosphonate tetraethyl ester
EINECS	Contact for details

Quality Control

Our Tetraethyl(Troc-Aminomethylene)Bisphosphonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Handle and store in accordance with all applicable local and international regulations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.