Description

Diethyl (Ethoxymethyl)Phosphonate is a versatile organophosphorus compound that serves as a key synthetic intermediate in the production of complex molecules. Its primary value lies in its role as a Horner-Wadsworth-Emmons (HWE) reagent, enabling the efficient formation of carbon-carbon double bonds, particularly in the synthesis of α,β-unsaturated esters and related compounds. This makes it an essential building block for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), especially those containing vinyl or acrylate moieties.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators.
• Specialty Chemical Manufacturing: Serves as a precursor for flame retardants, plasticizers, and other functional additives.
• Material Science Research: Employed in the development of novel polymers, ligands for catalysis, and organic electronic materials.
• Academic & R&D Laboratories: A fundamental reagent for organic synthesis, particularly in methodologies involving olefination reactions.
• Flavor and Fragrance Industry: Can be utilized in the synthesis of certain aroma chemicals and flavoring agents.

Basic Information

Product Name	Diethyl (Ethoxymethyl)Phosphonate
CAS No.	10419-80-4
Molecular Formula	C7H17O4P
Molecular Weight	196.18 g/mol
Synonyms	(Ethoxymethyl)phosphonic Acid Diethyl Ester; Diethyl Ethoxymethylphosphonate; Diethyl P-(Ethoxymethyl)phosphonate; Ethoxymethanephosphonic Acid Diethyl Ester; NSC 88431; Phosphonic Acid, P-(Ethoxymethyl)-, Diethyl Ester; (Ethoxymethyl)-diethoxyphosphine Oxide
EINECS	233-896-2

Quality Control

Our Diethyl (Ethoxymethyl)Phosphonate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, NMR, and titration methods, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.425 - 1.435
Density (20°C)	1.08 - 1.12 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.