Description

Dimethyl Trimethylsilylmethylphosphonate is a versatile organosilicon phosphonate ester, a key reagent in modern synthetic chemistry. Its primary value lies in its dual functionality, serving as a protected phosphonate anion equivalent and a silyl transfer agent, enabling complex molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise carbon-phosphorus bond formation and silicon-based protecting group strategies.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing phosphonate or bisphosphonate moieties for therapeutic applications.
• Horner-Wadsworth-Emmons (HWE) Reagent: Used as a stabilized phosphonate ylide precursor for olefination reactions to construct alkenes with high stereoselectivity, valuable in fine chemical synthesis.
• Agrochemical Synthesis: Employed in the production of advanced herbicides, plant growth regulators, and other crop protection agents that incorporate phosphonate functional groups.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized phosphonate-based ligands used in coordination chemistry and homogeneous catalysis.
• Material Science Research: Utilized in the development of flame-retardant additives, surface modifiers, and novel polymers where silicon and phosphorus synergism is desired.
• Process Chemistry & Scale-up: Valued for its stability and handling properties in multi-step industrial synthesis under both batch and continuous flow conditions.

Basic Information

Product Name	Dimethyl Trimethylsilylmethylphosphonate
CAS No.	13433-42-6
Molecular Formula	C7H19O3PSi
Molecular Weight	210.29 g/mol
Synonyms	Dimethyl (Trimethylsilyl)methylphosphonate; (Trimethylsilyl)methylphosphonic Acid Dimethyl Ester; Phosphonic Acid, P-[(Trimethylsilyl)methyl]-, Dimethyl Ester; Dimethyl (Trimethylsilylmethyl)phosphonate; (Dimethoxyphosphoryl)methyltrimethylsilane; TMSMDP
EINECS	Contact for details

Quality Control

Our Dimethyl Trimethylsilylmethylphosphonate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing including GC, NMR, and Karl Fischer titration to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain purity and prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.