Description

3-Oxobutylphosphonic Acid Diethyl Ester is a versatile organophosphorus compound that serves as a key synthetic intermediate. Its value lies in its bifunctional structure, featuring both a reactive ketone and a phosphonate ester group, enabling its use in various carbon-carbon bond-forming reactions. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity building blocks for complex molecule synthesis.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing phosphonate or β-ketophosphonate moieties.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that leverage its phosphonate functionality.
• Horner-Wadsworth-Emmons (HWE) Reaction Reagent: Acts as a stabilized carbanion equivalent for the stereoselective synthesis of alkenes, a fundamental transformation in organic chemistry.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of specialized phosphonate-based ligands used in coordination chemistry and catalysis.
• Material Science Research: Employed in the development of novel polymers, flame retardants, and metal-chelating agents.
• Chemical Synthesis Building Block: Utilized in academic and industrial R&D for constructing complex molecular architectures through its reactive sites.

Basic Information

Product Name	3-Oxobutylphosphonic Acid Diethyl Ester
CAS No.	1067-90-9
Molecular Formula	C8H17O4P
Molecular Weight	208.19 g/mol
Synonyms	Diethyl (3-oxobutyl)phosphonate; Diethyl 3-Oxobutylphosphonate; 4-(Diethoxyphosphoryl)butan-2-one; 3-Oxobutylphosphonic Acid Diethyl Ester; Acetylpropylphosphonic Acid Diethyl Ester; Butan-2-one, 4-(diethoxyphosphinyl)-; Diethyl Acetylpropylphosphonate; (3-Oxobutyl)phosphonic Acid Diethyl Ester
EINECS	213-937-8

Quality Control

Our 3-Oxobutylphosphonic Acid Diethyl Ester is produced and tested under a rigorous quality management system. Each batch is analyzed to ensure it meets stringent purity and consistency standards, with specifications tailored to application needs from research to production scale. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The product is moisture-sensitive; ensure containers are kept tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.430 - 1.440
Density (20°C)	1.08 - 1.12 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.