Description

Succinyl Phosphonate Trisodium Salt is a high-purity, organophosphorus compound of significant interest in biochemical and pharmaceutical research. Its primary value lies in its potent and selective inhibitory activity against key metabolic enzymes, particularly succinyl-CoA synthetase, making it a crucial tool for studying cellular energy metabolism. This compound is essential for researchers and developers in the life sciences, pharmaceutical R&D, and biotechnology sectors who require precise biochemical probes for target validation and pathway analysis.

Application

• Biochemical Research: As a potent and specific inhibitor of succinyl-CoA synthetase (SCS) for studying the tricarboxylic acid (TCA) cycle, glyoxylate cycle, and ketone body metabolism.
• Pharmaceutical Development: A valuable tool compound for target validation and high-throughput screening in drug discovery programs targeting metabolic disorders, cancer, and bacterial infections.
• Enzymology Studies: Used to investigate enzyme kinetics, mechanism of action, and the role of succinyl-CoA in various anabolic and catabolic pathways.
• Microbiology Research: Applied in studies of bacterial metabolism, as the succinyl-CoA pathway is critical for many pathogens, offering potential avenues for novel antibiotic development.
• Diagnostic Reagent Intermediate: Serves as a key synthetic intermediate or reference standard in the development of diagnostic assays and kits related to metabolic function.
• Academic Research: A standard reagent in university and institutional labs for graduate and post-doctoral research focused on bioenergetics and metabolic engineering.

Basic Information

Product Name	Succinyl Phosphonate Trisodium Salt
CAS No.	864167-45-3
Molecular Formula	C4H4Na3O7P
Molecular Weight	279.99 g/mol
Synonyms	SPT; Succinyl Phosphonate Sodium Salt; Trisodium Succinyl Phosphonate; (3-Carboxy-1-phosphonopropyl)phosphonic Acid Trisodium Salt; Succinyl CoA Synthetase Inhibitor; SCS Inhibitor; NSC 119911; 1,4-Dicarboxy-2-phosphonobutane Trisodium Salt
EINECS	Contact for details

Quality Control

Our Succinyl Phosphonate Trisodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.