Description

Butanoic Acid, Ethyldimethylsilyl Ester is a specialized organosilicon derivative of butyric acid, serving as a valuable silylating agent and synthetic intermediate. This compound is engineered to introduce the ethyldimethylsilyl (EDMS) protecting group, offering enhanced stability and reactivity profiles for advanced organic synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the protection of sensitive functional groups and the synthesis of novel silicon-containing molecules.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) where the EDMS group protects hydroxyl or carboxyl groups during multi-step reactions.
• Agrochemical Synthesis: Serves as a key building block for creating novel pesticides and herbicides with improved stability and efficacy.
• Material Science Precursor: Employed in the development of silicone-based polymers, coatings, and advanced materials with tailored surface properties.
• Organic Synthesis Reagent: Acts as a versatile silylating agent in laboratory-scale and pilot-scale organic chemistry for the protection of alcohols, acids, and other nucleophiles.
• Flavor & Fragrance Chemistry: Utilized in the controlled synthesis of esters and other compounds for high-value aroma chemicals.
• Cross-Coupling Reactions: Functions as a reagent in palladium-catalyzed and other metal-mediated coupling reactions to construct complex molecular architectures.

Basic Information

Product Name	Butanoic Acid, Ethyldimethylsilyl Ester
CAS No.	959019-24-0
Molecular Formula	C8H18O2Si
Molecular Weight	174.31 g/mol
Synonyms	Ethyldimethylsilyl Butyrate; Butyric Acid Ethyldimethylsilyl Ester; EDMS-Butyrate; Ethyldimethylsilyl Butanoate; 1-(Ethyldimethylsilyloxy)butane-1-one; (Ethyldimethylsilyl) butanoate; Butanoic acid O-(ethyldimethylsilyl) ester
EINECS	Contact for details

Quality Control

Our Butanoic Acid, Ethyldimethylsilyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.