Description

1,3-Cyclohexadiene, 1,4-Dimethyl-2-[(Trimethylsilyl)oxy]- is a specialized organosilicon compound featuring a cyclohexadiene backbone functionalized with a silyl-protected hydroxyl group. This unique structure makes it a valuable protected intermediate or building block in advanced organic synthesis, particularly for the construction of complex molecules where controlled reactivity is essential. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the multi-step synthesis of complex drug candidates, leveraging the reactivity of the diene and the protected alcohol.
• Organometallic Chemistry: Acts as a ligand precursor or a substrate in catalytic reactions involving transition metals.
• Polymer & Material Science: Used in the development of specialty polymers, resins, or silicon-containing hybrid materials with tailored properties.
• Agrochemical Research: Employed as a building block for creating novel active ingredients in crop protection agents.
• Academic & Industrial R&D: A valuable reagent for methodological studies in synthetic organic chemistry, including cycloaddition and functionalization reactions.

Basic Information

Product Name	1,3-Cyclohexadiene, 1,4-Dimethyl-2-[(Trimethylsilyl)oxy]-
CAS No.	958319-66-9
Molecular Formula	C11H20OSi
Molecular Weight	196.36 g/mol
Synonyms	2-[(Trimethylsilyl)oxy]-1,4-dimethyl-1,3-cyclohexadiene; 1,4-Dimethyl-2-(trimethylsiloxy)-1,3-cyclohexadiene; 1,3-Cyclohexadiene, 1,4-dimethyl-2-(trimethylsilyl)oxy]-; TMS-protected 1,4-dimethyl-1,3-cyclohexadien-2-ol; 2-(Trimethylsiloxy)-1,4-dimethyl-1,3-cyclohexadiene
EINECS	Contact for details

Quality Control

Every batch of 1,3-Cyclohexadiene, 1,4-Dimethyl-2-[(Trimethylsilyl)oxy]- is produced and analyzed under strict quality management protocols. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as verified by GC, HPLC, and NMR. Our quality systems are designed to support cGMP and ISO standards for research and development applications, ensuring traceability and consistency for critical synthetic pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.