Description

2,3,4,6-Tetra-o-Pivaloyl-β-D-Glucopyranosyl Isothiocyanate is a high-purity, protected glycosyl donor derivative, specifically engineered for advanced synthetic chemistry applications. This compound is a critical reagent for the stereoselective synthesis of thioglycosides and glycoconjugates, offering superior stability and reactivity compared to unprotected precursors. It is essential for researchers and process chemists in pharmaceutical development, agrochemical synthesis, and carbohydrate chemistry who require reliable building blocks for complex molecule assembly.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel glycosylated drug candidates, including antibiotics and anticancer agents.
• Glycoconjugate Synthesis: Used in the preparation of structurally defined thioglycosides for biological studies and vaccine development.
• Agrochemical Research: Serves as a precursor for creating sugar-based bioactive molecules with potential herbicidal or insecticidal properties.
• Chemical Biology Probes: Enables the labeling and study of carbohydrate-protein interactions through its reactive isothiocyanate group.
• Process Chemistry: Employed in scalable routes for the production of complex oligosaccharides and natural product analogs.
• Academic Research: A valuable tool in synthetic organic chemistry laboratories for methodology development and total synthesis projects.

Basic Information

Product Name	2,3,4,6-Tetra-o-Pivaloyl-β-D-Glucopyranosyl Isothiocyanate
CAS No.	958300-06-6
Molecular Formula	C27H43NO9S
Molecular Weight	557.70 g/mol
Synonyms	2,3,4,6-Tetra-O-pivaloyl-β-D-glucopyranosyl isothiocyanate; Pivaloyl-protected glucosyl isothiocyanate; Tetra-O-pivaloyl-β-D-glucopyranosyl isothiocyanate; β-D-Glucopyranosyl isothiocyanate, 2,3,4,6-tetrakis(2,2-dimethylpropanoyl)-; Glc(β)-NCS, Piv-protected; 1-Isothiocyanato-2,3,4,6-tetra-O-pivaloyl-β-D-glucopyranose
EINECS	Contact for details

Quality Control

Our 2,3,4,6-Tetra-o-Pivaloyl-β-D-Glucopyranosyl Isothiocyanate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.