Description

Phenyl Isothiocyanate is a versatile organic reagent widely used in peptide sequencing and organic synthesis. This compound is valued for its role as a key derivatization agent in the Edman degradation process, enabling the stepwise identification of amino acids. It is essential for research and production in pharmaceutical development, biotechnology, and advanced material science, where precise chemical modification is required.

Application

• Peptide Sequencing (Edman Degradation): Primary reagent for the step-by-step identification of amino-terminal residues in peptides and proteins.
• Pharmaceutical Intermediates: Used in the synthesis of various active pharmaceutical ingredients (APIs) and heterocyclic compounds.
• Bioconjugation & Labeling: Acts as a coupling agent for modifying biomolecules, including proteins and antibodies, for diagnostic and research applications.
• Polymer Chemistry: Serves as a monomer or modifier in the production of specialized polymers and resins.
• Agricultural Chemical Synthesis: Intermediate in the manufacture of certain herbicides, fungicides, and plant growth regulators.
• Analytical Chemistry: Employed as a derivatizing agent in chromatography (HPLC, GC) for the detection and quantification of amines and amino acids.

Basic Information

Product Name	Phenyl Isothiocyanate
CAS No.	103-72-0
Molecular Formula	C7H5NS
Molecular Weight	135.19 g/mol
Synonyms	PITC; Isothiocyanatobenzene; Phenyl mustard oil; Thiocarbanil; Benzene, isothiocyanato-; Phenylcarbimide; NSC 8646; Phenyl isosulfocyanate
EINECS	203-138-1

Quality Control

Our Phenyl Isothiocyanate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including assay (HPLC), identity confirmation (IR, NMR), and impurity profiling to ensure it meets the high-purity standards required for research and industrial applications. Certificates of Analysis (COA) are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area at room temperature (15-25°C). Due to its highly volatile and light-sensitive nature, containers should be kept tightly sealed when not in use to prevent evaporation and degradation.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.648 - 1.652
Density (20°C)	1.128 - 1.132 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.