Description

4-Bromobenzyl Isothiocyanate is a versatile organic building block characterized by its reactive isothiocyanate (-N=C=S) functional group attached to a 4-bromobenzyl moiety. This compound matters for its role as a key intermediate in the synthesis of more complex molecules, particularly in pharmaceutical research and agrochemical development. It is primarily needed by R&D chemists and process development scientists in the life sciences, fine chemical, and material science industries for constructing novel heterocycles and functionalized derivatives.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential drug candidates, especially those targeting various enzymes and receptors.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides by incorporating the thiourea or related motifs.
• Chemical Biology Probe: Acts as an electrophilic warhead for labeling cysteine residues in proteins, useful for activity-based protein profiling (ABPP) and proteomics studies.
• Material Science: Employed in the synthesis of functional polymers, ligands for metal-organic frameworks (MOFs), and advanced organic materials.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and for creating libraries of compounds for high-throughput screening.

Basic Information

Product Name	4-Bromobenzyl Isothiocyanate
CAS No.	10219-19-9
Molecular Formula	C8H6BrNS
Molecular Weight	228.11 g/mol
Synonyms	1-(Isothiocyanatomethyl)-4-bromobenzene; p-Bromobenzyl Isothiocyanate; 4-Bromobenzyl Mustard Oil; (4-Bromophenyl)methyl Isothiocyanate; NSC 401122; 4-Bromobenzylisothiocyanate; α-Isothiocyanato-4-bromotoluene
EINECS	Contact for details

Quality Control

Our 4-Bromobenzyl Isothiocyanate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.