Description

4-Isothiocyanatophenyl Ether is a specialized organic compound featuring a reactive isothiocyanate group linked via an ether bridge. This unique structure makes it a valuable bifunctional building block for synthesizing complex molecules, particularly in advanced material and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty polymer industries seeking to introduce thiourea or thiocarbamate linkages into their target compounds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition or requiring specific bio-conjugation.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and plant growth regulators where the isothiocyanate moiety imparts biological activity.
• Polymer Modification: Acts as a cross-linking agent or functional monomer for creating specialty polymers with enhanced thermal or chemical resistance.
• Bioconjugation Reagent: Facilitates the labeling and modification of proteins, peptides, and other biomolecules for diagnostic and research applications.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research: A versatile scaffold in organic synthesis for constructing heterocycles and other complex molecular architectures.

Basic Information

Product Name	4-Isothiocyanatophenyl Ether
CAS No.	10396-05-1
Molecular Formula	C14H9NOS
Molecular Weight	239.29 g/mol
Synonyms	1-Isothiocyanato-4-phenoxybenzene; p-Phenoxyphenyl isothiocyanate; 4-Phenoxyphenyl isothiocyanate; 1-Phenoxy-4-isothiocyanatobenzene; NSC 403119; Ether, 4-isothiocyanatophenyl; [4-(Isothiocyanato)phenoxy]benzene
EINECS	Contact for details

Quality Control

Our 4-Isothiocyanatophenyl Ether is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets precise customer specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment, guaranteeing traceability and consistent high quality for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as amines, alcohols, and oxidizing agents. The container must be kept tightly sealed due to moisture sensitivity and potential reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.