Description

4-(Trifluoromethyl)Phenyl Isothiocyanate is a specialized aromatic isothiocyanate derivative, distinguished by the presence of a trifluoromethyl group. This compound is a critical building block in advanced organic synthesis, valued for its ability to introduce both the phenyl isothiocyanate moiety and fluorine atoms into target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry, material science, and as a precursor for heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of biologically active molecules, including potential kinase inhibitors and other therapeutic agents.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging the stability imparted by the trifluoromethyl group.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialized polymers and advanced materials.
• Chemical Biology: Employed as a labeling reagent or probe in bioconjugation chemistry due to its reactive isothiocyanate group.
• Ligand Synthesis: Building block for creating complex ligands used in catalysis and coordination chemistry.
• Research & Development: A versatile reagent for academic and industrial R&D exploring new synthetic pathways and compound libraries.

Basic Information

Product Name	4-(Trifluoromethyl)Phenyl Isothiocyanate
CAS No.	1645-65-4
Molecular Formula	C8H4F3NS
Molecular Weight	203.19 g/mol
Synonyms	p-(Trifluoromethyl)phenyl isothiocyanate; 1-Isothiocyanato-4-(trifluoromethyl)benzene; 4-Trifluoromethylphenyl isothiocyanate; α,α,α-Trifluoro-p-tolyl isothiocyanate; 4-(Trifluoromethyl)benzenisothiocyanate; NSC 404082; (4-Trifluoromethylphenyl)isothiocyanate
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethyl)Phenyl Isothiocyanate is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use and stored away from heat sources and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.