Description

Azd1152 CAS NO 957881-03-7 is a potent and selective Aurora B kinase inhibitor, a key compound in targeted cancer therapy research. Its primary value lies in its ability to precisely inhibit cell division, making it a critical tool for investigating novel oncology treatments and understanding tumor biology. This high-purity biochemical is essential for pharmaceutical R&D, academic research, and biotechnology companies focused on developing next-generation anticancer agents.

Application

• Oncology Research: A key investigational compound for studying the role of Aurora B kinase in tumor cell proliferation and apoptosis.
• Drug Discovery & Development: Used as a reference standard and active pharmaceutical ingredient (API) in preclinical studies for novel anticancer therapeutics.
• Biochemical Assays: Employed in high-throughput screening (HTS) and in vitro kinase assays to evaluate compound efficacy and selectivity.
• Mechanistic Studies: Facilitates research into mitotic regulation, chromosomal segregation, and the mechanisms of action of kinase inhibitors.
• Pharmaceutical Intermediates: Serves as a critical building block in the synthesis of more complex therapeutic candidates.

Basic Information

Product Name	Azd1152
CAS No.	957881-03-7
Molecular Formula	C₂₆H₃₃FN₈O₃
Molecular Weight	524.59 g/mol
Synonyms	AZD-1152; AZD1152; Barasertib; Barasertib (AZD1152); 5-[2-(Ethyl{3-[4-(2-methyl-2H-indazol-6-yl)anilino]quinoxalin-2-yl}amino)ethyl]thiophene-2-carboxamide; (S)-5-[2-[Ethyl-[3-[4-(2-methylindazol-6-yl)anilino]-2-quinoxalyl]amino]ethyl]thiophene-2-carboxamide; HQPA; AZD 1152 HQPA.
EINECS	Contact for details

Quality Control

Our Azd1152 is manufactured under strict quality management systems to ensure the highest standards of purity and consistency, suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support your regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere to prevent degradation. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.