Description

20-Azido-3,6,9,12,15,18-Hexaoxaeicosan-1-Amine is a specialized bifunctional PEG linker featuring a reactive amine group and an azide moiety, enabling efficient conjugation and click chemistry applications. This compound is critical for researchers and manufacturers requiring precise, stable, and biocompatible cross-linking in advanced material and life science applications. It is primarily utilized in bioconjugation, polymer chemistry, and the development of drug delivery systems and diagnostic probes.

Application

• Bioconjugation and Protein/Peptide Labeling: Used to attach fluorescent dyes, drugs, or other functional molecules to biomolecules via amine-reactive chemistry and subsequent click reactions.
• Polymer and Dendrimer Synthesis: Serves as a versatile building block for creating functionalized polymers with tailored properties for biomedical applications.
• Surface Modification and Functionalization: Enables the grafting of bioactive ligands or polymers onto material surfaces (e.g., nanoparticles, chips, medical devices) to enhance biocompatibility or introduce specific functions.
• Drug Delivery System Development: Facilitates the creation of targeted drug conjugates and smart nanocarriers by linking therapeutic payloads to targeting ligands or PEG shells.
• Diagnostic Probe and Biosensor Fabrication: Employed in the assembly of sensitive detection platforms, such as immunoassays or molecular imaging agents.
• Click Chemistry Reagent: The azide group readily participates in copper-catalyzed azide-alkyne cycloaddition (CuAAC) or strain-promoted reactions for modular assembly of complex architectures.
• Hydrogel and Biomaterial Cross-linking: Used to form stable, biocompatible networks for tissue engineering scaffolds or controlled release matrices.

Basic Information

Product Name	20-Azido-3,6,9,12,15,18-Hexaoxaeicosan-1-Amine
CAS No.	957486-82-7
Molecular Formula	C14H28N4O6
Molecular Weight	348.40 g/mol
Synonyms	Azido-PEG6-Amine; N3-PEG6-NH2; 20-Azido-3,6,9,12,15,18-hexaoxaeicosan-1-amine; Azido-PEG6-Amine; 1-Amino-20-azido-3,6,9,12,15,18-hexaoxaeicosane; Azidohexaethylene glycol amine; Amine-PEG6-Azide; NH2-PEG6-N3
EINECS	Contact for details

Quality Control

Our 20-Azido-3,6,9,12,15,18-Hexaoxaeicosan-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.