Description

3-(4-Azidophenyl)Propionic Acid is a specialized aromatic carboxylic acid derivative featuring a reactive azido functional group. This bifunctional molecule is critical for click chemistry applications, enabling efficient and selective bioconjugation under mild, aqueous conditions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotech, and materials science sectors for labeling, cross-linking, and surface modification.

Application

• Bioconjugation & Click Chemistry: A key reagent for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions to label biomolecules like proteins, antibodies, and oligonucleotides.
• Pharmaceutical Research: Used in the synthesis of antibody-drug conjugates (ADCs) and for attaching fluorescent probes or other payloads to drug candidates for targeted delivery and imaging.
• Polymer & Materials Science: Serves as a functional monomer or cross-linker for creating smart polymers, hydrogels, and surface-modified nanomaterials with specific biological or chemical properties.
• Proteomics & Bioanalytics: Employed in activity-based protein profiling (ABPP) and other chemical proteomics strategies to study enzyme function and discover new drug targets.
• Diagnostic Assay Development: Facilitates the stable immobilization of capture molecules (e.g., antigens, DNA) onto various solid supports for ELISA, microarray, and biosensor platforms.

Basic Information

Product Name	3-(4-Azidophenyl)Propionic Acid
CAS No.	103489-31-2
Molecular Formula	C9H9N3O2
Molecular Weight	191.19 g/mol
Synonyms	4-Azidohydrocinnamic Acid; 3-(4-Azidophenyl)propanoic Acid; p-Azidohydrocinnamic Acid; 3-(4-Azidophenyl)propionic Acid; 4-Azidobenzene propanoic Acid; Azido-PEG1-acid; Azidophenylpropionic Acid
EINECS	Contact for details

Quality Control

Our 3-(4-Azidophenyl)Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and degradation. Allow the container to reach room temperature in a desiccator before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.