Description

3-Azido-3-Methylbutanoic Acid is a versatile bifunctional organic building block containing both an azido group and a carboxylic acid moiety. This unique structure makes it a valuable intermediate for click chemistry applications, particularly in the synthesis of complex molecules and bioconjugates. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing novel compounds and functional materials.

Application

• Click Chemistry Intermediate: A key precursor for Huisgen 1,3-dipolar cycloaddition reactions with alkynes to form 1,2,3-triazoles.
• Pharmaceutical Research: Used in the synthesis of potential drug candidates, prodrugs, and for bioconjugation to create antibody-drug conjugates (ADCs).
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating functional polymers with tailored properties.
• Agrochemical Development: Employed in the design and synthesis of novel active ingredients and intermediates.
• Proteomics & Bioconjugation: Facilitates the labeling and modification of proteins, peptides, and other biomolecules for research and diagnostic purposes.
• Chemical Biology Probes: Acts as a building block for creating activity-based probes and other tools to study biological systems.

Basic Information

Product Name	3-Azido-3-Methylbutanoic Acid
CAS No.	105090-72-0
Molecular Formula	C5H9N3O2
Molecular Weight	143.14 g/mol
Synonyms	3-Azido-3-methylbutyric acid; 3-Methyl-3-azidobutanoic acid; 3-Azido-3-methyl-butyric acid; 3-Azido-3-methylbutanoic acid; 3-Azido-3-methylbutyric acid; 3-Methyl-3-azidobutanoic acid; (3-Azido-3-methylbutyryl) group; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 3-Azido-3-Methylbutanoic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and may require storage under an inert atmosphere for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.