Description

3-Azido-2-Chloropyridine is a versatile heterocyclic building block featuring both an azido group and a chloro substituent on the pyridine ring. This bifunctional structure makes it a critical intermediate for click chemistry applications and the synthesis of complex nitrogen-containing compounds. It is primarily used by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of triazole-linked drug candidates via copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with enhanced biological activity.
• Material Science & Polymer Chemistry: Used to functionalize polymers and surfaces, introducing azide groups for subsequent cross-linking or labeling reactions.
• Bioconjugation & Probe Development: Facilitates the labeling of biomolecules (proteins, nucleic acids) for diagnostic and research applications.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing novel nitrogen-donor ligands used in catalysis.
• Academic & Contract Research: Essential reagent for methodological development in organic and medicinal chemistry research.

Basic Information

Product Name	3-Azido-2-Chloropyridine
CAS No.	102934-51-0
Molecular Formula	C5H3ClN4
Molecular Weight	154.56 g/mol
Synonyms	2-Chloro-3-azidopyridine; 3-Azido-2-chloropyridine; 2-Chloro-3-pyridyl azide; 3-Azidopyridine, 2-chloro-; 2-Chloro-3-azidopyridine; 3-Azido-2-chloro-pyridine; Azidopyridine derivative
EINECS	Contact for details

Quality Control

Our 3-Azido-2-Chloropyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system adheres to cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to the presence of the azido functional group, handle and store away from strong heat sources and incompatible materials. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area%)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.