Description

Methanone, (4-Bromophenyl)(4,4-Difluoro-1-Piperidinyl)- is a specialized organic building block featuring a bromophenyl ketone core functionalized with a difluorinated piperidine moiety. This compound is valued for its unique molecular architecture, which makes it a critical intermediate in advanced pharmaceutical and agrochemical research and development. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for constructing complex molecules, particularly in the synthesis of potential drug candidates and bioactive agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the biological activity of the difluoropiperidine group.
• Material Science: Serves as a precursor for advanced organic materials, including ligands for catalysis and monomers for specialty polymers.
• Chemical Biology: Employed as a probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis and scale-up projects.

Basic Information

Item	Details
Product Name	Methanone, (4-Bromophenyl)(4,4-Difluoro-1-Piperidinyl)-
CAS No.	955406-30-1
Molecular Formula	C12H12BrF2NO
Molecular Weight	304.13 g/mol
Synonyms	(4-Bromophenyl)(4,4-difluoropiperidin-1-yl)methanone; 1-(4-Bromobenzoyl)-4,4-difluoropiperidine; 4,4-Difluoro-1-(4-bromobenzoyl)piperidine; 4-Bromophenyl 4,4-difluoropiperidin-1-yl ketone; 955406-30-1; AKOS005258213; BRN 15305835
EINECS	Contact for details

Quality Control

Every batch of Methanone, (4-Bromophenyl)(4,4-Difluoro-1-Piperidinyl)- is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.