Description

3'-Bromo-4'-Fluoroacetophenone is a high-purity halogenated acetophenone derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of bromine and fluorine atoms on the aromatic ring, which enables precise functionalization for creating complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging the bioactivity of the halogenated aromatic system.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated and brominated organic electronic materials.
• Cross-Coupling Reactions: The bromine atom acts as an excellent handle for palladium-catalyzed reactions like Suzuki, Stille, or Negishi couplings.
• Functional Material Research: Employed in academic and industrial R&D for creating novel polymers and ligands with specific electronic properties.
• Custom Synthesis & Contract Manufacturing: A vital raw material for fine chemical companies offering bespoke synthesis services.

Basic Information

Product Name	3'-Bromo-4'-Fluoroacetophenone
CAS No.	1007-15-4
Molecular Formula	C8H6BrFO
Molecular Weight	217.04 g/mol
Synonyms	1-(3-Bromo-4-fluorophenyl)ethanone; 3-Bromo-4-fluoroacetophenone; 1-Acetyl-3-bromo-4-fluorobenzene; 3'-Bromo-4'-fluoroacetophenone; 3-Bromo-4'-fluoroacetophenone; 4-Fluoro-3-bromoacetophenone; Ethanone, 1-(3-bromo-4-fluorophenyl)-; 3-Bromo-4-fluorophenyl methyl ketone
EINECS	Contact for details

Quality Control

Our 3'-Bromo-4'-Fluoroacetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.