Description

2,2-Dibromo-1-thiophen-2-yl-ethanone is a specialized brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its highly reactive α,α-dibromo ketone moiety, which serves as a versatile precursor for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel thiophene-containing drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides with thiophene cores.
• Material Science Research: Serves as a precursor for developing functional polymers, organic semiconductors, and conductive materials.
• Organic Synthesis Reagent: Employed in cyclization reactions, heterocycle formation, and as an electrophile in C-C bond-forming reactions under palladium catalysis.
• Chemical Biology Probes: Useful for synthesizing molecular probes and inhibitors for studying biological pathways and enzyme functions.

Basic Information

Product Name	2,2-Dibromo-1-thiophen-2-yl-ethanone
CAS No.	68672-88-8
Molecular Formula	C6H4Br2OS
Molecular Weight	291.97 g/mol
Synonyms	2,2-Dibromo-1-(2-thienyl)ethanone; 2,2-Dibromo-2-thienyl-ethanone; 2-Thienylglyoxal Dibromide; 2,2-Dibromoacetylthiophene; α,α-Dibromo-2-acetylthiophene; 2-(Dibromoacetyl)thiophene; 1-(Thiophen-2-yl)-2,2-dibromoethanone
EINECS	Contact for details

Quality Control

Our 2,2-Dibromo-1-thiophen-2-yl-ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.