Description

1-(4-Bromophenyl)-2-Methylpropan-1-One is a versatile brominated aromatic ketone intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key building block for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing aryl ketone or biphenyl motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the bromophenyl group.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the creation of organic semiconductors, liquid crystals, and advanced polymers where bromine acts as a functional handle for further cross-coupling reactions.
• Chemical Research & Development: A valuable building block for method development in cross-coupling reactions like Suzuki, Heck, and Stille couplings.

Basic Information

Product Name	1-(4-Bromophenyl)-2-Methylpropan-1-One
CAS No.	49660-93-7
Molecular Formula	C10H11BrO
Molecular Weight	227.10 g/mol
Synonyms	4'-Bromoisobutyrophenone; p-Bromoisobutyrophenone; 1-(4-Bromophenyl)-2-methyl-1-propanone; 2-Methyl-1-(4-bromophenyl)propan-1-one; α,α-Dimethyl-4-bromoacetophenone; 4-Bromo-α,α-dimethylacetophenone; Isobutyryl-4-bromobenzene
EINECS	Contact for details

Quality Control

Our 1-(4-Bromophenyl)-2-Methylpropan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, purity, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.