Description

3'-Chloro-4'-Fluoro-3-(3-Fluorophenyl)Propiophenone is a high-purity fluorinated aromatic ketone intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a critical building block in the development of complex, biologically active molecules, particularly within the pharmaceutical sector. It is primarily needed by research institutions and chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its specific halogenated structure enables precise molecular modifications.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where fluorinated compounds enhance stability and bioactivity.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals that require specific fluorinated aromatic units.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, such as Suzuki or Heck reactions, to construct complex polycyclic aromatic systems.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	3'-Chloro-4'-Fluoro-3-(3-Fluorophenyl)Propiophenone
CAS No.	898767-29-8
Molecular Formula	C15H11ClF2O
Molecular Weight	280.70 g/mol
Synonyms	1-(3-Chloro-4-fluorophenyl)-3-(3-fluorophenyl)-1-propanone; 3-(3-Fluorophenyl)-1-(3-chloro-4-fluorophenyl)propan-1-one; 3'-Chloro-4'-fluoro-3-(3-fluorophenyl)propiophenone; 898767-29-8; Propiophenone, 3'-chloro-4'-fluoro-3-(3-fluorophenyl)-; 1-Propanone, 1-(3-chloro-4-fluorophenyl)-3-(3-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our 3'-Chloro-4'-Fluoro-3-(3-Fluorophenyl)Propiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.