Description

2-Bromo-4'-Bromomethylacetophenone is a versatile brominated aromatic ketone building block of significant importance in advanced organic synthesis. Its bifunctional bromomethyl and bromoaryl structure makes it a critical precursor for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is essential for chemists and manufacturers engaged in the development of active pharmaceutical ingredients (APIs), liquid crystal materials, and specialized fine chemicals, where precise functionalization is required.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in kinase inhibitor and anti-cancer agent research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging its reactive sites for molecular diversification.
• Liquid Crystal Materials: Serves as a building block for mesogenic compounds used in display technologies.
• Polymer Chemistry: Acts as a cross-linking agent or functional monomer for specialty polymers with tailored properties.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions.
• Material Science Research: Utilized in the development of organic semiconductors and photoactive materials.

Basic Information

Product Name	2-Bromo-4'-Bromomethylacetophenone
CAS No.	62546-51-4
Molecular Formula	C9H8Br2O
Molecular Weight	291.97 g/mol
Synonyms	1-(4-(Bromomethyl)phenyl)-2-bromoethanone; 2-Bromo-1-[4-(bromomethyl)phenyl]ethanone; 4'-Bromomethyl-2-bromoacetophenone; α,4'-Dibromoacetophenone; p-Bromomethyl-α-bromoacetophenone; BBAP; NSC 403914
EINECS	Contact for details

Quality Control

Our 2-Bromo-4'-Bromomethylacetophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.