Description

Mk-1775 is a high-purity, small molecule chemical compound with significant research and development applications. This product is valued for its role as a potent and selective inhibitor, making it a critical tool in biochemical and pharmacological studies. It is primarily utilized by research institutions and pharmaceutical companies engaged in oncology and targeted therapy development. We supply this compound globally with a focus on consistent quality and reliable availability for the scientific community.

Application

• Biochemical Research: Used as a selective inhibitor in enzymatic assays and pathway analysis studies.
• Pharmaceutical R&D: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in early-stage drug discovery programs.
• Oncology Research: Investigated for its mechanism of action in cell-based studies targeting specific cancer pathways.
• Preclinical Studies: Employed in in vitro and in vivo models to evaluate efficacy and pharmacokinetic properties.
• Chemical Synthesis: Acts as a building block or intermediate for the synthesis of more complex molecular entities.

Basic Information

Item	Detail
Product Name	Mk-1775
CAS No.	955365-80-7
Molecular Formula	C17H14Br2N4O3
Molecular Weight	490.13 g/mol
Synonyms	AZD-1775; MK-1775; Adavosertib; 2-Allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-((4-(4-methylpiperazin-1-yl)phenyl)amino)-1H-pyrazolo[3,4-d]pyrimidin-3(2H)-one; 6-(2-Hydroxypropan-2-yl)-2-{2-[(4-{4-[(4-methylpiperazin-1-yl)carbonyl]piperazin-1-yl}phenyl)amino]-1,3-benzothiazol-6-yl}-2,3-dihydro-1H-isoindol-1-one (common salt form reference); WEE1 Inhibitor MK-1775
EINECS	Contact for details

Quality Control

Our Mk-1775 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.