Description

(5-Chloro-Thiophen-2-Yl)-Cyclobutyl-Methanone is a high-purity organic building block featuring a chlorinated thiophene moiety linked to a cyclobutyl ketone, a structure of significant interest in advanced synthetic chemistry. This compound matters as a versatile and critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Active Ingredient Development: Used in the research and production of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the chlorothiophene scaffold.
• Material Science Research: Acts as a precursor for functionalized polymers and organic electronic materials due to the electron-rich thiophene ring system.
• Chemical Biology & Proteomics: Employed as a building block for creating molecular probes and affinity tags to study biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	(5-Chloro-Thiophen-2-Yl)-Cyclobutyl-Methanone
CAS No.	955126-39-3
Molecular Formula	C9H9ClOS
Molecular Weight	200.68 g/mol
Synonyms	5-Chloro-2-cyclobutanoylthiophene; Cyclobutyl(5-chloro-2-thienyl)methanone; (5-Chloro-2-thienyl)cyclobutylmethanone; 5-Chlorothiophene-2-cyclobutyl ketone; 2-Cyclobutanoyl-5-chlorothiophene; 5-Chloro-2-thiophenecarboxylic acid cyclobutyl ketone; 955126-39-3 (CAS Registry)
EINECS	Contact for details

Quality Control

Our (5-Chloro-Thiophen-2-Yl)-Cyclobutyl-Methanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.