Description

4-Oxo-n-{3-[(3-Pyridinylcarbonyl)Amino]Propyl}-3,4-Dihydro-2-Quinazolinecarboxamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value in medicinal chemistry research and development, particularly for its role as a key building block in synthesizing novel therapeutic agents. It is primarily sought by R&D teams and process chemists in the pharmaceutical and biotechnology industries for the development of targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel quinazoline and pyridine-based drug candidates.
• Kinase Inhibitor Research: Serves as a core scaffold for the development of potential kinase inhibitors targeting various disease pathways.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization processes.
• Biochemical Research: Employed as a reference standard or probe compound in biochemical and pharmacological assays.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for exploratory research in organic and medicinal chemistry.

Basic Information

Product Name	4-Oxo-n-{3-[(3-Pyridinylcarbonyl)Amino]Propyl}-3,4-Dihydro-2-Quinazolinecarboxamide
CAS No.	954293-58-4
Molecular Formula	C₁₈H₁₇N₅O₃
Molecular Weight	351.36 g/mol
Synonyms	N-(3-((Nicotinamido)propyl)-4-oxo-3,4-dihydroquinazoline-2-carboxamide; 2-Quinazolinecarboxamide, 3,4-dihydro-4-oxo-N-[3-[(3-pyridinylcarbonyl)amino]propyl]-; 954293-58-4; UNII-6J2A0F4J9C; 6J2A0F4J9C; CHEMBL3186033; AKOS015915889; ZINC000003869176
EINECS	Contact for details

Quality Control

Our 4-Oxo-n-{3-[(3-Pyridinylcarbonyl)Amino]Propyl}-3,4-Dihydro-2-Quinazolinecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.