Description

7-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Tetrahydrofuran-2-Yl)-5-Fluoro-3H-Pyrrolo[2,3-D]Pyrimidin-4(7H)-One (Wx130402) is a high-purity nucleoside analog, a key building block in advanced pharmaceutical research and development. Its primary value lies in its role as a sophisticated synthetic intermediate for the creation of novel antiviral and anticancer therapeutics. This compound is essential for research institutions, pharmaceutical companies, and CDMOs (Contract Development and Manufacturing Organizations) engaged in the synthesis of modified nucleosides and oligonucleotides.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel antiviral and anticancer drug candidates.
• Antiviral Research: Used in the development of nucleotide analogs targeting viral polymerases.
• Oncology Research: Serves as a building block for creating nucleoside-based chemotherapeutic agents.
• Oligonucleotide Synthesis: Employed in the production of modified antisense oligonucleotides and siRNA.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleic acid metabolism.
• Process Development: Supports scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	7-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Tetrahydrofuran-2-Yl)-5-Fluoro-3H-Pyrrolo[2,3-D]Pyrimidin-4(7H)-One (Wx130402)
CAS No.	952429-17-3
Molecular Formula	C11H13FN4O5
Molecular Weight	300.24 g/mol
Synonyms	5-Fluoro-7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one; 5-Fluoro-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-ol; 5-Fluorotubercidin; Wx130402; 5-Fluoro-7-(β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidin-4(7H)-one; 5-Fluoro-7-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-ol; 5-Fluorotubercidin ribonucleoside
EINECS	Contact for details

Quality Control

Our 7-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Tetrahydrofuran-2-Yl)-5-Fluoro-3H-Pyrrolo[2,3-D]Pyrimidin-4(7H)-One (Wx130402) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements or regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.