Description

1-(4-Bromobenzyl)-5-Methyl-1H-[1,2,3]-Triazole-4-Carbonyl Chloride is a high-value, reactive chemical intermediate designed for advanced synthetic applications. This compound is critical for researchers and manufacturers requiring precise functionalization in complex molecular architectures. It is primarily utilized by the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of antiviral, anticancer, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging the triazole and bromobenzyl motifs.
• Material Science Research: Serves as a precursor for functional polymers, ligands for metal-organic frameworks (MOFs), and other specialty materials.
• Chemical Biology Probes: Employed in the creation of activity-based probes and biochemical tools due to its reactive carbonyl chloride group.
• Peptide & Protein Modification: Acts as a coupling agent or labeling reagent for modifying biomolecules in bioconjugation chemistry.
• Academic & Industrial R&D: Essential reagent for method development and exploratory synthesis in organic and medicinal chemistry laboratories.

Basic Information

Product Name	1-(4-Bromobenzyl)-5-Methyl-1H-[1,2,3]-Triazole-4-Carbonyl Chloride
CAS No.	952182-50-2
Molecular Formula	C11H9BrClN3O
Molecular Weight	314.57 g/mol
Synonyms	1-[(4-Bromophenyl)methyl]-5-methyl-1H-1,2,3-triazole-4-carbonyl chloride; 5-Methyl-1-(4-bromobenzyl)-1H-1,2,3-triazole-4-carbonyl chloride; 1-(4-Bromobenzyl)-5-methyl-1,2,3-triazole-4-carboxylic acid chloride; 952182-50-2; 1-(4-Bromobenzyl)-5-methyl-1H-[1,2,3]triazole-4-carbonyl chloride; 1H-1,2,3-Triazole-4-carbonyl chloride, 1-[(4-bromophenyl)methyl]-5-methyl-
EINECS	Contact for details

Quality Control

Our production of 1-(4-Bromobenzyl)-5-Methyl-1H-[1,2,3]-Triazole-4-Carbonyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All material is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We operate under a cGMP-compliant quality management system, and specifications can be tailored to meet the rigorous standards of pharmaceutical (ICH Q3A/B) and advanced chemical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.