Description

2-Bromo-3′,5′-Difluorobenzophenone is a high-purity, multi-functional organic intermediate of significant importance in advanced chemical synthesis. Its core value lies in its unique halogenated and fluorinated benzophenone structure, which makes it a critical building block for creating complex molecules with tailored properties. This compound is primarily needed by research and development laboratories and production facilities in the pharmaceutical, agrochemical, and material science industries, where it serves as a key precursor for active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine atoms for enhanced bioactivity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a key starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes (OLEDs).
• Polymer Modification Agent: Employed to introduce bromine and fluorine functional groups into polymer chains, altering physical properties like thermal stability, solubility, and flame retardancy.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck), enabling the construction of complex biaryl structures.
• Organic Synthesis Research: A valuable reagent for academic and industrial chemists exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	2-Bromo-3′,5′-Difluorobenzophenone
CAS No.	951891-77-3
Molecular Formula	C₁₃H₇BrF₂O
Molecular Weight	297.10 g/mol
Synonyms	(2-Bromophenyl)(3,5-difluorophenyl)methanone; 3',5'-Difluoro-2-bromobenzophenone; Benzophenone, 2-bromo-3',5'-difluoro-; 2-Bromo-3,5-difluorobenzophenone; 1-(2-Bromophenyl)-2-(3,5-difluorophenyl)ethanone (common misnomer); 2-Bromo-3,5-difluorobenzoylbenzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-3′,5′-Difluorobenzophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.