Description

3,4-Difluoro-3'-Iodobenzophenone is a high-purity, multi-functional organic intermediate featuring both fluorine and iodine substituents on a benzophenone core. This compound is valued for its unique reactivity profile, enabling precise structural modifications in advanced synthetic pathways. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those requiring halogenated aromatic systems for bioactivity or metabolic stability.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the difluoro and iodo groups contribute to binding affinity and environmental persistence.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic electronic materials.
• Ligand Synthesis: Employed in the preparation of sophisticated ligands for catalysis, leveraging the halogen atoms for further functionalization.
• Chemical Biology Probes: Utilized as a scaffold for creating molecular probes and tags due to the handle provided by the iodine atom for further conjugation (e.g., via Sonogashira or Suzuki coupling).
• Academic & Industrial R&D: A versatile reagent for methodological development and exploring new chemical spaces in organic synthesis laboratories worldwide.

Basic Information

Product Name	3,4-Difluoro-3'-Iodobenzophenone
CAS No.	951891-71-7
Molecular Formula	C13H7F2IO
Molecular Weight	344.10 g/mol
Synonyms	(3'-Iodophenyl)(3,4-difluorophenyl)methanone; 3,4-Difluoro-3'-iodobenzophenone; 3'-Iodo-3,4-difluorobenzophenone; Methanone, (3,4-difluorophenyl)(3-iodophenyl)-; Benzophenone, 3,4-difluoro-3'-iodo-; 3,4-Difluoro-3-iodobenzophenone (common alternate numbering); CAS 951891-71-7
EINECS	Contact for details

Quality Control

Our 3,4-Difluoro-3'-Iodobenzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (HPLC), impurity profile, and physical characteristics. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and should be handled under an inert atmosphere if prolonged exposure is anticipated to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.