Description

3,4-Difluoro-2'-Iodobenzophenone is a high-purity, multi-functional organic building block featuring both fluorine and iodine substituents on a benzophenone core. This compound is valued for its versatility in advanced organic synthesis, particularly in the construction of complex molecules for pharmaceutical and agrochemical research. It serves as a critical intermediate for medicinal chemists and R&D professionals developing new active ingredients, where its unique halogen pattern enables precise structural modifications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially in kinase inhibitor and CNS-active compound research.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the fluorine and iodine atoms for bioactivity and metabolic stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorinated Compound Library: A valuable starting material for creating diverse fluorinated compound libraries for high-throughput screening in drug discovery.
• Chemical Biology Probes: Used to synthesize photoaffinity labeling agents or other molecular probes due to the reactive iodine handle.

Basic Information

Product Name	3,4-Difluoro-2'-Iodobenzophenone
CAS No.	951891-68-2
Molecular Formula	C13H7F2IO
Molecular Weight	344.10 g/mol
Synonyms	2'-Iodo-3,4-difluorobenzophenone; (2-Iodophenyl)(3,4-difluorophenyl)methanone; 3,4-Difluoro-2-iodobenzophenone; Benzophenone, 3,4-difluoro-2'-iodo-; 951891-68-2; 2-Iodobenzophenone, 3',4'-difluoro derivative
EINECS	Contact for details

Quality Control

Our 3,4-Difluoro-2'-Iodobenzophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates, and we support our clients' regulatory filing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%
Solubility	Soluble in common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.