Description

2-Bromo-3′-Chloro-5′-Fluorobenzophenone is a high-purity, multi-halogenated benzophenone derivative serving as a critical advanced pharmaceutical intermediate. Its value lies in its unique halogen substitution pattern, which provides versatile reactivity for constructing complex molecular scaffolds in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals due to its rigid, halogenated benzophenone core.
• Organic Synthesis: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution, enabling complex molecule construction.
• Chemical Reference Standard: Utilized in analytical laboratories for method development and quality control of related substances.

Basic Information

Product Name	2-Bromo-3′-Chloro-5′-Fluorobenzophenone
CAS No.	951890-40-7
Molecular Formula	C13H7BrClFO
Molecular Weight	313.55 g/mol
Synonyms	2-Bromo-3'-Chloro-5'-Fluorobenzophenone; (2-Bromophenyl)(3-chloro-5-fluorophenyl)methanone; 3-Chloro-5-fluoro-2-bromobenzophenone; Benzophenone, 2-bromo-3'-chloro-5'-fluoro-; 951890-40-7
EINECS	Contact for details

Quality Control

Our 2-Bromo-3′-Chloro-5′-Fluorobenzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.