Description

(2-Bromo-5-Fluorophenyl)(Pyrrolidin-1-Yl)Methanone is a high-value fluorinated and brominated aromatic ketone derivative, serving as a critical building block in advanced organic synthesis. Its unique bifunctional halogenated structure makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine and bromine atoms contribute to biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for synthesizing specialty polymers, liquid crystals, and organic electronic materials due to its aromatic and halogenated framework.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	(2-Bromo-5-Fluorophenyl)(Pyrrolidin-1-Yl)Methanone
CAS No.	951884-12-1
Molecular Formula	C11H11BrFNO
Molecular Weight	272.11 g/mol
Synonyms	1-(2-Bromo-5-fluorophenyl)-1-pyrrolidinylmethanone; 1-(2-Bromo-5-fluorobenzoyl)pyrrolidine; 2-Bromo-5-fluoro-N-pyrrolidinylbenzamide; (2-Bromo-5-fluorobenzoyl)pyrrolidine; Pyrrolidine, 1-(2-bromo-5-fluorobenzoyl)-; 951884-12-1; 2-Bromo-5-fluorophenyl pyrrolidin-1-yl methanone
EINECS	Contact for details

Quality Control

Our (2-Bromo-5-Fluorophenyl)(Pyrrolidin-1-Yl)Methanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.