Description

Ethanone, 1-(2,4-Difluoro-3-Hydroxyphenyl)- is a high-purity, fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a ketone and a hydroxyl group on a difluorinated benzene ring, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in fluorinated compound libraries.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the difluorophenol moiety enhances biological activity and stability.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its rigid, fluorinated aromatic core.
• Chemical Research & Development: Employed in organic synthesis for constructing complex molecular architectures via reactions at the ketone and phenolic hydroxyl functional groups.
• Fluorine Chemistry Studies: A valuable compound for investigating structure-activity relationships (SAR) and the effects of fluorine substitution in aromatic systems.

Basic Information

Product Name	Ethanone, 1-(2,4-Difluoro-3-Hydroxyphenyl)-
CAS No.	951163-65-8
Molecular Formula	C8H6F2O2
Molecular Weight	172.13 g/mol
Synonyms	1-(2,4-Difluoro-3-hydroxyphenyl)ethanone; 2',4'-Difluoro-3'-hydroxyacetophenone; 3'-Hydroxy-2',4'-difluoroacetophenone; 2,4-Difluoro-3-hydroxyacetophenone; 1-Acetyl-2,4-difluoro-3-hydroxybenzene; DFHA
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(2,4-Difluoro-3-Hydroxyphenyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.