Description

1H-Indole-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its value lies in its role as a versatile building block for constructing complex heterocyclic molecules, enabling the development of novel compounds with targeted properties. This product is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel indole-based drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators with indole core structures.
• Material Science: Serves as a precursor for creating specialty polymers and advanced organic electronic materials.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in heterocyclic chemistry.
• Peptide Mimetics: Employed in the design and synthesis of peptidomimetics and other bioactive molecules.
• Ligand Synthesis: Used to prepare complex ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	1H-Indole-4-Carbonyl Chloride
CAS No.	949899-70-1
Molecular Formula	C9H6ClNO
Molecular Weight	179.60 g/mol
Synonyms	Indole-4-carbonyl chloride; 4-Carboxyindole chloride; 1H-Indole-4-carboxylic acid chloride; 4-Indolecarbonyl chloride; 4-(Chlorocarbonyl)-1H-indole; 1H-Indole-4-carbonyl chloride; 949899-70-1; 4-Indolylcarbonyl chloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for high-purity chemical intermediates. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and IR spectroscopy to confirm identity and purity. Certificates of Analysis (COA) detailing all test results are available upon request, providing full traceability and batch-specific data to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.