Description

Ethanone, 1-(4-Fluoro-3-Hydroxyphenyl)- is a high-purity fluorinated aromatic ketone building block, identified by CAS NO 949159-95-9. This compound is valued for its unique molecular structure, which combines a ketone functional group with a fluorinated hydroxyphenyl moiety, making it a versatile intermediate for advanced synthesis. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and inflammatory diseases.
• Agrochemical Synthesis: Serves as a crucial building block for the synthesis of advanced herbicides, fungicides, and plant growth regulators, leveraging the bioactivity of the fluorinated aromatic system.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its rigid molecular structure and potential for derivatization.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation in pharmaceutical and chemical analysis.
• Organic Synthesis Building Block: Utilized in academic and industrial R&D for constructing complex molecules via reactions such as Friedel-Crafts acylation, Suzuki coupling, and nucleophilic aromatic substitution.

Basic Information

Item	Detail
Product Name	Ethanone, 1-(4-Fluoro-3-Hydroxyphenyl)-
CAS No.	949159-95-9
Molecular Formula	C8H7FO2
Molecular Weight	154.14 g/mol
Synonyms	1-(4-Fluoro-3-hydroxyphenyl)ethanone; 4'-Fluoro-3'-hydroxyacetophenone; 3-Hydroxy-4-fluoroacetophenone; 4-Fluoro-3-hydroxyacetophenone; 1-Acetyl-4-fluoro-3-hydroxybenzene; 4-Fluoro-3-acetylphenol; 949159-95-9; 4-Fluoro-3-hydroxyphenyl methyl ketone
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(4-Fluoro-3-Hydroxyphenyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with REACH and other global regulatory frameworks, and custom synthesis to meet specific pharmacopeial or internal standards is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.