Description

2-Chloro-N6-(2-Hydroxyethyl)Adenosine is a chemically modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a versatile and critical building block for the synthesis of novel therapeutic agents, particularly in the fields of oncology and antiviral drug discovery. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in creating next-generation adenosine receptor-targeting drugs and nucleotide-based prodrugs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel adenosine receptor agonists and antagonists for cardiovascular and neurological research.
• Antiviral Prodrug Development: Used in the research and development of nucleotide analog prodrugs targeting viral polymerases.
• Oncology Research: Serves as a building block for creating investigational anti-cancer agents that modulate cellular signaling pathways.
• Biochemical Tool Compound: Utilized in life science research to study adenosine-mediated processes and receptor interactions.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for specialized, high-value chemical entities.
• Academic Research: Fundamental research compound in universities and institutes studying nucleoside chemistry and medicinal chemistry.

Basic Information

Product Name	2-Chloro-N6-(2-Hydroxyethyl)Adenosine
CAS No.	948298-76-8
Molecular Formula	C12H16ClN5O5
Molecular Weight	345.74 g/mol
Synonyms	2-Chloro-N6-(2-hydroxyethyl)adenosine; 2-Cl-N6-(2-hydroxyethyl)adenosine; 2-Chloro-N(6)-(2-hydroxyethyl)adenosine; N6-(2-Hydroxyethyl)-2-chloroadenosine; 2-Chloro-N6-(2-hydroxyethyl)-9-β-D-ribofuranosyladenine; Adenosine, 2-chloro-N6-(2-hydroxyethyl)-; 948298-76-8
EINECS	Contact for details

Quality Control

Our 2-Chloro-N6-(2-Hydroxyethyl)Adenosine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.