Description

2-Bromo-4-(Trifluoromethoxy)Isothiocyanate is a specialized organic building block characterized by its reactive isothiocyanate and bromo-trifluoromethoxy substitution pattern. This compound is of significant value in advanced chemical synthesis, particularly for constructing heterocyclic scaffolds and introducing sulfur-containing functional groups. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders and metabolic diseases.
• Agrochemical Research: Used in the development of next-generation herbicides and fungicides, leveraging its unique halogenated structure for bioactivity.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialized polymers with tailored thermal and chemical resistance.
• Chemical Biology Probe: Utilized for bioconjugation and labeling of biomolecules due to the high reactivity of the isothiocyanate group with amines.
• Organic Synthesis Building Block: Enables the construction of complex heterocycles like thiazoles and benzothiazines for various research applications.

Basic Information

Product Name	2-Bromo-4-(Trifluoromethoxy)Isothiocyanate
CAS No.	948294-38-0
Molecular Formula	C8H3BrF3NOS
Molecular Weight	298.08 g/mol
Synonyms	2-Bromo-4-(trifluoromethoxy)phenyl isothiocyanate; 1-Bromo-4-isothiocyanato-2-(trifluoromethoxy)benzene; 2-Bromo-α,α,α-trifluoro-p-isothiocyanatoanisole; Benzene, 1-bromo-4-isothiocyanato-2-(trifluoromethoxy)-; Isothiocyanic acid, 2-bromo-4-(trifluoromethoxy)phenyl ester
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-(Trifluoromethoxy)Isothiocyanate is manufactured and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.