Description

2,2-Dibromo-5,6-Difluoro-2,3-Dihydro-1H-Inden-1-One is a high-purity, halogenated indanone derivative serving as a critical advanced intermediate in organic synthesis. Its unique dibromo-difluoro substitution pattern makes it a valuable building block for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable synthetic intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated and brominated drug candidates, potentially for central nervous system (CNS) agents, anti-inflammatory drugs, or enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, or pesticides where the difluoro and dibromo motifs can enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, or organic electronic materials.
• Chemical Biology & Proteomics: Can be utilized as a reactive handle or scaffold for creating chemical probes, enzyme substrates, or inhibitors in biochemical research.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and cyclization reactions to introduce halogenated indanone cores into more complex molecules.

Basic Information

Product Name	2,2-Dibromo-5,6-Difluoro-2,3-Dihydro-1H-Inden-1-One
CAS No.	947753-65-3
Molecular Formula	C9H4Br2F2O
Molecular Weight	337.94 g/mol
Synonyms	2,2-Dibromo-5,6-difluoroindan-1-one; 5,6-Difluoro-2,2-dibromo-2,3-dihydro-1H-inden-1-one; 1H-Inden-1-one, 2,2-dibromo-5,6-difluoro-2,3-dihydro-; 2,2-Dibromo-5,6-difluoro-1-indanone; DBDFI (abbreviation); 947753-65-3; 5,6-Difluoro-2,2-dibromoindan-1-one
EINECS	Contact for details

Quality Control

Our 2,2-Dibromo-5,6-Difluoro-2,3-Dihydro-1H-Inden-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for pharmaceutical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.