Description

4-Chloro-2-Fluoro-5-Nitrobenzoyl Chloride is a high-value, multi-functional aromatic acid chloride intermediate. This compound matters for its role as a critical building block in the synthesis of complex, biologically active molecules, offering precise reactivity for introducing specific functional groups. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry for creating amide and ester derivatives.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging its halogenated nitrobenzene structure.
• Ligand and Material Science: Serves as a starting material for synthesizing specialized ligands for catalysis and advanced organic materials.
• Peptide Coupling Reagent: Functions as an activating agent in peptide synthesis and other coupling reactions requiring acyl chloride functionality.
• Dyestuff and Pigment Intermediate: Employed in the production of complex dyes and high-performance pigments.
• Custom Synthesis and R&D: Essential for contract research organizations (CROs) and fine chemical companies engaged in custom synthesis projects.

Basic Information

Product Name	4-Chloro-2-Fluoro-5-Nitrobenzoyl Chloride
CAS No.	947311-91-3
Molecular Formula	C7H2Cl2FNO3
Molecular Weight	252.00 g/mol
Synonyms	5-Nitro-2-fluoro-4-chlorobenzoyl chloride; 2-Fluoro-4-chloro-5-nitrobenzoyl chloride; 4-Chloro-2-fluoro-5-nitrobenzoic acid chloride; Benzoyl chloride, 4-chloro-2-fluoro-5-nitro-; 947311-91-3; 4-Chloro-2-fluoro-5-nitro-benzoyl chloride
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Fluoro-5-Nitrobenzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizers, and sources of ignition.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.