Description

n-[(3-Hydroxyphenyl)Methyl]-5'-Adenylic Acid is a chemically modified nucleotide analog that serves as a valuable building block in advanced biochemical research and pharmaceutical development. This compound is significant for its role in the synthesis of novel nucleoside derivatives and as a potential precursor for enzyme inhibitors or prodrugs. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, nucleotide-based drug discovery, and the development of targeted therapeutic agents.

Application

• Medicinal Chemistry Research: A key intermediate in the synthesis of novel adenosine receptor ligands or nucleotide-based prodrugs.
• Biochemical Probe Development: Used to create labeled or modified nucleotides for studying enzyme mechanisms and metabolic pathways.
• Pharmaceutical Intermediates: Serves as a precursor in the multi-step synthesis of potential antiviral or anticancer agents.
• Enzyme Inhibition Studies: Investigated for its potential to modulate the activity of kinases, polymerases, or other nucleotide-binding enzymes.
• Academic Research: Utilized in universities and research institutes for fundamental studies in bioorganic chemistry and chemical biology.

Basic Information

Product Name	n-[(3-Hydroxyphenyl)Methyl]-5'-Adenylic Acid
CAS No.	946853-27-6
Molecular Formula	C17H19N5O7P
Molecular Weight	460.34 g/mol
Synonyms	5'-Adenylic Acid, N-[(3-hydroxyphenyl)methyl]-; N-(3-Hydroxybenzyl)adenosine 5'-monophosphate; 3-Hydroxybenzyl-AMP; Adenosine 5'-monophosphate, N-(3-hydroxybenzyl) derivative; 946853-27-6; N-(3-Hydroxybenzyl)-AMP; 5'-O-Phosphono-N-[(3-hydroxyphenyl)methyl]adenosine
EINECS	Contact for details

Quality Control

Our n-[(3-Hydroxyphenyl)Methyl]-5'-Adenylic Acid is produced under a strict quality management system to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable for pharmaceutical intermediates, and specifications can be aligned with client requirements for advanced research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Identification (IR)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.