Description

5-(Carboxyhydroxymethyl)Uridine Methyl Ester is a chemically modified nucleoside derivative, serving as a crucial building block and intermediate in advanced organic synthesis. This compound is valued for its role in the development of novel pharmaceuticals, nucleotide analogs, and biochemical research tools. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in antiviral drug development, oligonucleotide synthesis, and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel nucleoside-based antiviral and anticancer agents.
• Biochemical Research: Used as a modified building block for studying RNA structure, function, and for developing nucleotide analogs.
• Oligonucleotide Synthesis: Serves as a protected monomer for the solid-phase synthesis of modified oligonucleotides for diagnostic and therapeutic applications.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize drug potency and metabolic stability.
• Fine Chemical Production: Intermediate for manufacturing specialized chemicals used in life science research and diagnostics.

Basic Information

Product Name	5-(Carboxyhydroxymethyl)Uridine Methyl Ester
CAS No.	945684-13-9
Molecular Formula	C12H16N2O8
Molecular Weight	316.26 g/mol
Synonyms	5-Carboxyhydroxymethyluridine Methyl Ester; 5-(Hydroxymethyl)-O2,2'-anhydrouridine-5'-carboxylic Acid Methyl Ester; Uridine, 5-(carboxyhydroxymethyl)-, methyl ester; 5-(Carboxymethylol)uridine Methyl Ester; Methyl 5-(hydroxymethyl)-2,2'-anhydro-1-(β-D-ribofuranosyl)uracil-5-carboxylate
EINECS	Contact for details

Quality Control

Our 5-(Carboxyhydroxymethyl)Uridine Methyl Ester is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide full traceability and Certificates of Analysis (COA) are available upon request to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.