Description

Amg 900 CAS NO 945595-80-2 is a potent and selective small molecule inhibitor targeting specific cellular pathways critical for research and development. This compound is valued for its high purity and consistent performance, making it an essential tool for advancing scientific discovery. It is primarily utilized by researchers and developers in the pharmaceutical and biotechnology sectors for target validation, mechanism-of-action studies, and preclinical investigations.

Application

• Biochemical Research: Used as a selective kinase inhibitor in enzymatic assays to study signal transduction pathways.
• Cell Biology Studies: Applied in cell culture models to investigate the effects of pathway inhibition on cell proliferation, apoptosis, and differentiation.
• Pharmaceutical R&D: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel therapeutic agents.
• Target Validation: Employed in functional genomics and phenotypic screening to confirm the role of specific molecular targets in disease models.
• Preclinical Development: Utilized in animal studies to evaluate the pharmacokinetics, pharmacodynamics, and efficacy of potential drug candidates.

Basic Information

Product Name	Amg 900
CAS No.	945595-80-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	AMG-900; AMG 900; Aurora Kinase Inhibitor AMG 900; 4-[(9-Chloro-7-(2-fluorophenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl)amino]-2-methoxybenzoic Acid; (S)-4-((9-Chloro-7-(2-fluorophenyl)-5H-benzo[c]pyrimido[4,5-e]azepin-2-yl)amino)-2-methoxybenzoic Acid
EINECS	Contact for details

Quality Control

Our Amg 900 is manufactured under strict quality management systems to ensure the highest standards of purity and consistency. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and potency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with our rigorous specifications. We support research and development with material traceable to cGMP-grade standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.