Description

Famitinib CAS NO 945380-27-8 is a potent and selective small-molecule inhibitor targeting multiple receptor tyrosine kinases. This compound is of significant interest in pharmaceutical research and development due to its potential therapeutic applications. It is primarily utilized by research institutions and pharmaceutical companies engaged in oncology drug discovery and preclinical studies.

Application

• Oncology Research: Primary application in the investigation of anti-tumor efficacy for various cancer types.
• Kinase Profiling: Used as a reference standard in biochemical assays to study kinase inhibition profiles and selectivity.
• Preclinical Development: Serves as a key active pharmaceutical ingredient (API) intermediate in the development of novel therapeutic candidates.
• Mechanistic Studies: Employed in cellular and molecular biology research to elucidate signaling pathways involved in cell proliferation and survival.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related substances.

Basic Information

Product Name	Famitinib
CAS No.	945380-27-8
Molecular Formula	C₂₄H₂₅FN₄O₃
Molecular Weight	436.48 g/mol
Synonyms	Famitinib; Famitinib (L); (S)-N-(2-(Diethylamino)ethyl)-N-(4-((4-((3-fluorophenyl)ethynyl)quinazolin-6-yl)oxy)phenyl)cyclopropane-1,1-dicarboxamide; UNII-9V78R8WU17; 9V78R8WU17; BIBF 1120; SHR-1020; Famitinib L-malate
EINECS	Contact for details

Quality Control

Our Famitinib is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and related substances, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.