Description

2-Bromo-1-(1-Methyl-1H-Benzimidazol-5-Yl)Ethanone Hydrobromide is a high-purity, advanced pharmaceutical intermediate with the CAS number 944450-78-6. This compound is a critical building block in the synthesis of complex molecules, valued for its precise reactivity and structural role in forming heterocyclic frameworks. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel benzimidazole-based drug candidates, particularly in oncology and antiviral research.
• Agrochemical Synthesis: Used in the development of new fungicides and herbicides that leverage the benzimidazole core for enhanced biological activity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and exploring new chemical reactions.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and process development projects.

Basic Information

Product Name	2-Bromo-1-(1-Methyl-1H-Benzimidazol-5-Yl)Ethanone Hydrobromide
CAS No.	944450-78-6
Molecular Formula	C10H10Br2N2O
Molecular Weight	350.01 g/mol
Synonyms	2-Bromo-1-(1-methyl-1H-benzimidazol-5-yl)ethanone hydrobromide; 5-Acetyl-1-methylbenzimidazole 2-bromoethanone hydrobromide; 1-(1-Methyl-1H-benzimidazol-5-yl)-2-bromoethanone HBr; 944450-78-6; α-Bromo-1-methyl-5-benzimidazolyl methyl ketone hydrobromide; 2-Bromo-1-(1-methyl-1H-benzo[d]imidazol-5-yl)ethan-1-one hydrobromide
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(1-Methyl-1H-Benzimidazol-5-Yl)Ethanone Hydrobromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere when not in use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.