Description

6-Bromo-8-Methoxy-2H-Benzo[B][1,4]Oxazin-3(4H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its distinct benzoxazinone core structure. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in research and development pipelines. It is primarily sought by pharmaceutical manufacturers and contract research organizations (CROs) engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders.
• Organic Synthesis Building Block: Used in research-scale and pilot-scale organic reactions to construct novel heterocyclic compounds.
• Agrochemical Research: Serves as a starting material for developing new candidates in crop protection and pesticide research.
• Material Science: Potential monomer or additive in the development of specialty polymers and advanced organic materials.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological studies and discovery chemistry.

Basic Information

Product Name	6-Bromo-8-Methoxy-2H-Benzo[B][1,4]Oxazin-3(4H)-One
CAS No.	943995-18-4
Molecular Formula	C9H8BrNO3
Molecular Weight	258.07 g/mol
Synonyms	6-Bromo-8-methoxy-3,4-dihydro-2H-1,4-benzoxazin-3-one; 6-Bromo-8-methoxy-2H-1,4-benzoxazin-3(4H)-one; 943995-18-4; 6-Bromo-8-methoxy-4H-1,4-benzoxazin-3-one; 6-Bromo-8-methoxy-3,4-dihydro-1,4-benzoxazin-3-one; 6-Bromo-8-methoxy-2H-benzo[b][1,4]oxazin-3(4H)-one; Benzoxazinone derivative, 6-bromo-8-methoxy-
EINECS	Contact for details

Quality Control

Our production of 6-Bromo-8-Methoxy-2H-Benzo[B][1,4]Oxazin-3(4H)-One adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with cGMP and ISO 9001 standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.